OCT Eye Scan Explained: Macula, Glaucoma and Diabetic Retinopathy

Optical coherence tomography images the retina in cross-section without contact. Learn its role in AMD, glaucoma and diabetic eye disease.

By Elements84 Medical Editorial TeamFeb 15, 2026 8 min readReviewed by
OCT Eye Scan Explained (oct eye scan) — nce tomography explained illustration
Quick Answer

OCT (optical coherence tomography) is a rapid, non-contact scan producing high-resolution cross-sections of the retina. It is now standard for diagnosing and monitoring wet AMD, diabetic macular oedema, macular hole, epiretinal membrane, and glaucoma (retinal nerve fibre layer thickness). NHS diabetic eye screening uses OCT for referable maculopathy.

Quick Reference

OCT has become the everyday backbone of retinal imaging. It uses low-coherence interferometry to build micron-resolution cross-sectional images of the retina and optic nerve head — non-contact, non-invasive, no radiation. Applications: (1) Age-related macular degeneration — detecting subretinal or intraretinal fluid triggers anti-VEGF injection therapy; treat-and-extend regimens rely on OCT. (2) Diabetic macular oedema — central retinal thickness > 300 µm triggers referral and treatment; NHS DES uses M1/M2 classifications. (3) Glaucoma — retinal nerve fibre layer (RNFL) and ganglion cell complex (GCC) thickness on Cirrus/Spectralis platforms track progression more sensitively than visual field. (4) Macular hole, epiretinal membrane, vitreomacular traction — surgical decisions. (5) Choroidal thickness — CSC and pachychoroid diseases. OCT angiography (OCT-A) adds vascular perfusion without dye, complementing fluorescein angiography in AMD and DR. Every optometrist practice in the UK now offers OCT; frequency 1–2 yearly for at-risk groups.

Key Facts
Radiation
None
Contact
None
Key uses
AMD, DMO, glaucoma, macular hole
AMD marker
Sub/intraretinal fluid
DMO threshold
Central retinal thickness > 300 µm

OCT in common conditions

ConditionOCT finding
Wet AMDSubretinal or intraretinal fluid
Diabetic macular oedemaIncreased central retinal thickness
GlaucomaThinning of RNFL and GCC
Macular holeFull-thickness break at the fovea
Epiretinal membraneThickened wrinkled internal limiting membrane

Who benefits

Anyone with sudden central vision distortion or scotoma — same-day OCT to exclude wet AMD.

Diabetic patients — annual OCT via NHS DES if maculopathy detected on retinal photography.

Glaucoma suspects and confirmed patients — baseline + serial monitoring.

Post-cataract patients with unexplained visual disturbance — check for cystoid oedema.

Get seen promptly if
  • Sudden vision loss or central distortion — same-day ophthalmology.
  • New macular fluid on OCT — anti-VEGF pathway.
  • Central retinal thickness rising on OCT + diabetes — treatment pathway.

When OCT changes management

  1. 1
    Central vision distortion?
    OCT to exclude wet AMD.
  2. 2
    Diabetic maculopathy on photos?
    OCT to grade.
  3. 3
    Glaucoma suspect?
    RNFL/GCC OCT + visual field.
  4. 4
    Unexplained post-op vision?
    OCT for cystoid oedema.

Frequently asked questions

Key takeaways
  • OCT is non-contact, radiation-free, and standard in modern eye care.
  • Detects AMD fluid, diabetic macular oedema, glaucoma thinning.
  • Every high-street optometrist now offers OCT in the UK.
  • Serial OCT drives anti-VEGF re-treatment.
  • OCT-angiography extends to vessels.

References

2 sources
  1. Royal College of OphthalmologistsClinical Guidelines

    UK ophthalmology.

    rcophth.ac.uk

  2. AAOPreferred Practice Patterns

    American Academy of Ophthalmology.

    aao.org

OCTOphthalmologyGlaucomaAMD
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